Rick Turner at Quintiles provides an overview of how one of the hottest areas in the treatment of hypertension concerns drug-resistant hypertension. Drug-resistant hypertension is commonly defined as blood pressure (BP) levels above a specified target despite a patient’s adherence to at least three optimally-dosed antihypertensive medications of different classes, including a diuretic. In addition to these requirements, Turner and O’Brien have recently argued that a patient should be on such a regimen for a minimum of three months before the classification is made. The methodology by which BP measurements are made also needs to be given careful consideration in this context.
https://international-pharma.com/wp-content/uploads/2013/10/Cardiovascular-Therapeutics.pdf