Current Edition

The Virtual Elaboration of Fragment Ideas – Dr Martin Slater, Cresset

Growing, Merging and Linking Fragments with Realistic Chemistry
Dr Robert Scoffin and Dr Martin Slater from Cresset serve readers with a fragment-based drug discovery article. Fragment-based drug discovery seeks to identify relatively simple and low molecular weight molecules which interact with protein targets, then grow or link them into active leads. Molecular design software can be used to create realistic chemistry between and around fragments.…pdf.pdf