Nipro Vialex – 26th January 2025
PCI – 7th June 2024
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Nasal & Pulmonary Drug Development
Novo Nordisk 20 March 2024, 11:21
Carterra – 24th March 2025

Combination Filling: The Trend Towards Machine Customisation

What is Combination Filling?
Combination filling refers to the process of placing two or more active ingredients within the same capsule. These ingredients can be in the form of powders, pellets, granules, liquids, tablets, micro-tablets, etc. allowing for a wide range of formulation possibilities. The goal is to create a single dose that delivers multiple therapeutic or nutritional benefits, improving patient or consumer convenience and compliance.

Combination filling is being utilised across a broad spectrum of applications in both the pharmaceutical and nutraceutical industries.

In pharmaceuticals, combination capsules are used to treat complex conditions that require multiple therapeutic approaches. For instance, cardiovascular medications often combine antihypertensive agents with cholesterol-lowering drugs to provide a more comprehensive treatment for heart disease.

In the nutraceutical sector, combination capsules are popular for wellness and preventive health. Products that combine antioxidants with vitamins, minerals, and herbal extracts are widely marketed for their holistic health benefits, targeting everything from immune support to cognitive function.

Combination filling is also making inroads into speciality supplements, such as sports nutrition and weight management products. These capsules often combine ingredients such as protein powders, amino acids and agents to support muscle growth, recovery, and fat loss.

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