Toxicology the study of poisons, determines whether a drug can be used on humans. Almost 30% of clinical trial attritions are attributed to the toxicological profile of a molecule. The patent cliff’s drying pipelines are driving the fail early and are failing safe practices in the drug development process. Meenakshi L at Beroe Inc., provides an overview of discovery toxicology and how this is being outsourced by the large pharma in bits and pieces owing to lack of efficiency in-house.
https://international-pharma.com/wp-content/uploads/2014/01/Discovery.pdf