Both the drug development process and fundamental studies of mechanisms underlying biological interactions require analytical methods that mimic the in vivo situation as much as possible. But this can be approached by using label-free cell-based assays. Davide Proverbio and Teodor Aastrup of Attana AB, and Jana Valnohova, Shane C. Wright and Gunnar Schulte of Karolinska Institutet, present a new cell-based assay that they developed for characterising interactions between peptides and their target receptors in a label-free environment.
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