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Optimising Short-Lived Isotopes for Quantitative Whole-Body Autoradiography in Drug Development

Quantitative whole-body autoradiography (QWBA), which has brought many improvements to the realm of tissue distribution, has itself been improved recently by the expanded use of short-lived isotopes. Andrea Knapp and Brian Knapp at MPI Research explain how this expansion increases options for better imaging and more specific data regarding tissue distribution due to increased resolution of QWBA images, as compared to PET or SPECT images.