The challenge of ensuring healthcare sustainability, the rise in more targeted treatments, and a shift in emphasis to preventative interventions, not to mention the importance of patient centricity in determining healthcare decisions, are creating a perfect storm for the transformation of healthcare systems and pharma’s role within them. Here, Gérard Klop of Vintura Consultancy explores how pharma’s new role will evolve in an increasingly value-based healthcare scenario. The challenges companies will encounter as they reinvent themselves and the cultural and organisational changes that will be required.