Pre-fillable syringes are both pharmaceutical primary packaging
and drug delivery devices. End users, drug administration agencies
and the pharmaceutical industry are imposing increasingly stringent
quality requirements on pre-fillable syringes in both these functions.
Optimised production and inspection processes ensure that the
syringes can meet these requirements. Although siliconisation is
crucial as lubricant to the proper function of the plunger in the
syringe body, it has to be reduced to the minimum in syringes used
for innovative biotech drugs. Bernd Zeiß and Claudia Petersen at
Gerresheimer look into the world of pre-fillable syringes.
https://international-pharma.com/wp-content/uploads/2016/07/Drug-3-Prefillable.pdf