Ready-to-fill, i.e. sterile, prefillable glass syringes, are washed, siliconised, sterilised and packaged by the primary packaging manufacturer. They can then be filled by the pharmaceutical companies without any further processing. These days the majority of prefillable syringes are made of glass and the trend looks set to continue. Within this article, Claudia Petersen and Bernd Zeiss from Gerresheimer deliver updates on syringe siliconisation trends, methods, and analysis procedures.