In drug discovery, data is king. Gathering the right information makes it easier to design better compounds, faster. How can you be sure that you are getting the most out of your SAR data? And how easy is it to see where the gaps are in your data? A typical lead optimisation phase of a drug discovery project will gather many thousands of data points. Hundreds, or even thousands, of compounds will be synthesised over the course of the project, and each of these compounds has an associated wealth of potency, selectivity and ADMET information. Katriona Scoffin and Giovanna Tedesco answers the question asked; where are the gaps in your data?